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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 13.94
Human Site: S992 Identified Species: 19.17
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 S992 Q Y T E E P L S Q E P S V D A
Chimpanzee Pan troglodytes XP_507923 1056 119132 S992 Q Y T E E P L S Q E P S V D A
Rhesus Macaque Macaca mulatta XP_001087644 853 96218 K792 N F N Q E G T K L V E E S V K
Dog Lupus familis XP_534964 1334 149091 V1273 G H S I E E P V S Q E S S K D
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 S988 Q C T E E L V S P E T T E H P
Rat Rattus norvegicus O55165 796 89797 D735 F S H D Q E Q D P R V L H M E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 E1136 E D Q T K D S E G S F K L E D
Frog Xenopus laevis P28025 1060 119314 S997 A V N D S V I S E R S C I D L
Zebra Danio Brachydanio rerio NP_775368 955 106984 T894 L G R V E M Q T S K D E A T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 S992 M H S V Q E L S E T E T I M N
Honey Bee Apis mellifera XP_623508 706 80766 Y645 K F F T E D L Y R D I P T G L
Nematode Worm Caenorhab. elegans P46873 699 78760 V638 A N S Y F K P V K Q I N V I N
Sea Urchin Strong. purpuratus P46872 699 78679 K638 T P V A D K D K S L A Y G E A
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 D994 H P S N K Q V D E P S C S T P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 E979 M P I E T L V E E F R E N N S
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 V1042 Q F S P K T P V P V P D Q P L
Red Bread Mold Neurospora crassa P48467 928 102392 G867 R L E A A K A G S T R G L G T
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 6.6 13.3 N.A. 40 0 N.A. N.A. 0 13.3 6.6 N.A. 13.3 13.3 6.6 6.6
P-Site Similarity: 100 100 20 33.3 N.A. 53.3 13.3 N.A. N.A. 26.6 40 20 N.A. 53.3 40 33.3 20
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 0 N.A. N.A. 6.6 13.3 0
P-Site Similarity: 26.6 N.A. N.A. 33.3 33.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 12 6 0 6 0 0 0 6 0 6 0 18 % A
% Cys: 0 6 0 0 0 0 0 0 0 0 0 12 0 0 0 % C
% Asp: 0 6 0 12 6 12 6 12 0 6 6 6 0 18 12 % D
% Glu: 6 0 6 24 42 18 0 12 24 18 18 18 6 12 6 % E
% Phe: 6 18 6 0 6 0 0 0 0 6 6 0 0 0 0 % F
% Gly: 6 6 0 0 0 6 0 6 6 0 0 6 6 12 0 % G
% His: 6 12 6 0 0 0 0 0 0 0 0 0 6 6 0 % H
% Ile: 0 0 6 6 0 0 6 0 0 0 12 0 12 6 0 % I
% Lys: 6 0 0 0 18 18 0 12 6 6 0 6 0 6 6 % K
% Leu: 6 6 0 0 0 12 24 0 6 6 0 6 12 0 24 % L
% Met: 12 0 0 0 0 6 0 0 0 0 0 0 0 12 0 % M
% Asn: 6 6 12 6 0 0 0 0 0 0 0 6 6 6 12 % N
% Pro: 0 18 0 6 0 12 18 0 18 6 18 6 0 6 12 % P
% Gln: 24 0 6 6 12 6 12 0 12 12 0 0 6 0 0 % Q
% Arg: 6 0 6 0 0 0 0 0 6 12 12 0 0 0 0 % R
% Ser: 0 6 30 0 6 0 6 30 24 6 12 18 18 0 6 % S
% Thr: 6 0 18 12 6 6 6 6 0 12 6 12 6 12 6 % T
% Val: 0 6 6 12 0 6 18 18 0 12 6 0 18 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 6 0 0 0 6 0 0 0 6 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _